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Name of the University : Pondicherry University
Name of the Exam : BINC Bioinformatics National Certification Examination
Subject: Paper – III
Document Type : Sample paper
Year : 2015
Website :
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BINC Examination Question Paper III :

Total Time : 2 hrs
Max. Marks:100
Note : Answer any one question.

Related : Pondicherry University BINC Examination Paper – II Question :

Input files provided : ( GENE.txt, 1mbi.pdb, autocat.dat, codontab.txt)
1. Write a program in JAVA or PERL or PYTHON or in C the followings:
a) Read the file provided ( GENE.txt in FASTA format ) and create complementary strand sequence.
b) Find the ORFs on forward strand for the given nucleotide sequence using only start & end codon pattern.
c) Convert each of the ORF into putative proteins using the standard codontab.txt (input provided).
d) Read the 1mbi.pdb as provided from protein data bank. Extract all the coordinates of water Oxygen atoms. Calculate the distance between all the Oxygen and Identify which one pairs will form Hydrogen bonds between them ( make a list by the residue number provided in PDB file starting form 160 to 278 ). ( 100 marks)

2. i) An autocatalytic reaction is described by the expression
x/P = [exp(at) -1]/ [1 + b exp(at)], with a= ( A +P)k and b = P/A.
Write a program in C or JAVA or Perl or PYTHON to calculate x/P for three values of t (t =1,2 and 3) using a & b as given in the input file autocat.dat.
Report if the saturation is reached by printing a string, “The saturation is reached. The values are” and then print the value of ( x/P, a, b and t) for the saturation point. Otherwise, print the message “ The Saturation is not reached” . All your output, including these messages is to be saved in a file called autocat.out. (30 marks)

ii) Read the 1mbi.pdb as provided from protein data bank. Extract all the peptide bond containing atoms (only non-H) make a list as output. Calculate the omega torsion angle for each of the peptides. Calculate the probability of occurrence of w= 180 from the resulting data. Calculate the ratio of polar : non polar residues in the protein . (70 marks )

BINC Bioinformatics National Certification Examination Details :

Eligibility :
** Bachelor degree in Life Sciences, Physical Sciences,Chemical Sciences,Mathematical Sciences, Agriculture, Veterinary, Medicine, Pharmacy, Engineering & Technology are eligible to appear in the examination. They need not have any formal training viz., certificate, diploma or degree in Bioinformatics.

** Students in final year of Bachelor & Post graduate degree are also eligible to apply.

Pattern of Examination :
** The examination consists of THREE papers.

Paper Type Date of Exam No. of questions Marks Duration Time
  Paper I     Objective
   March 23, 2017
(Morning session)
100 100 2 hours 10:00 – 12:00
  Paper II   Short answers   April 09, 2017
(Morning session)
20 200 3 hours 09:00 – 12:00
  Paper III   Practicals   April 09, 2017
(Afternoon session)
1 100 3 hours 14:00 – 17:00

Important points to note :
** For Paper I there will be negative marking of 0.25 for every wrong answer.
** The list of successful candidates in the Paper I will be announced on March 27, 2017 on the website.
** Candidates securing 40% or above marks in Paper I ONLY will be eligible to appear for Paper II and III.
** Candidates scoring a minimum of 40% or above in each papers(Paper I, Paper II & Paper III) will be certified.
** Final list will be displayed at the BINC website.

Steps for Registration for BINC 2017 are as follows :
** Register to create a Profile
** Login with system generated User ID and Password
** Submit Application, process payment (if applicable).
** Rs. 600 for General category, Rs. 400 for Women/OBC and Rs.200 for SC/ST candidates. Examination fee is waived for Physical Challenged candidates.

** Upon creating a profile, you will receive a User ID and Password on your registered email ID and mobile number. Using these credentials you can login as Registered Applicant to fill the Application form. The application may be saved at any stage and can be re-visited to complete later. Once the form is submitted, you will not be allowed to edit any details in the Application form.

Before you register, Kindly follow the instructions below :
1. Check your eligibility for BINC 2017 by referring to the advertisement on the website.
2. Ensure you have a valid email id and mobile number.
3. “*” (asterisk) indicates a mandatory field. The boxes marked with this symbol are mandatory.

4. Keep following information ready for filling the form :
a. Personal details
b. Qualifying Exam Mark sheets
c. Applicable Certificates to upload
d. Scanned images of your passport photo and signature (as per guidelines)

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