BME802 Modeling of Physiological System B.Tech Question Paper : wbut.ac.in
Name of the University : West Bengal University of Technology
Department : Biomedical Engineering
Degree : B.Tech
Sem : VIII
Subject Code/Name : BME-802/Modeling Of Physiological System
Website : wbut.ac.in
Document Type : Previous Year Examination Question Paper
Download Model/Sample Question Paper :
2009 : https://www.pdfquestion.in/uploads/qpaper.wbut.ac.in/6684-2009BME-802.pdf
2010 : https://www.pdfquestion.in/uploads/qpaper.wbut.ac.in/6684-2010BME-802%20.pdf
2011 : https://www.pdfquestion.in/uploads/qpaper.wbut.ac.in/6684-2011BME-802(1).pdf
2012 : https://www.pdfquestion.in/uploads/qpaper.wbut.ac.in/6684-2012BME-802(2).pdf
2013 : https://www.pdfquestion.in/uploads/qpaper.wbut.ac.in/6684-20132BME-8258(802).pdf
Modeling Of Physiological System Question Paper :
Engineering & Management Examinations, April – 2009 :
Semester – 8 :
Time : 3 Hours
Full Marks : 70
Related : West Bengal University of Technology BME801 Medical Image Processing B.Tech Question Paper : www.pdfquestion.in/6683.html
GROUP – A : ( Multiple Choice Type Questions )
1. Choose the correct alternatives for the following : 10 × 1 = 10
i) Compartmental models are
a) lumped model b) continuous time model
c) both (a) and (b) d) none of these.
ii) In electrical analogue model, pressure changes are considered as
a) current changes b) resistance changes
c) potential changes d) none of these.
iii) Neural network model is an example of
a) black box model
b) building block model
c) none of these.
iv) The cell membrane potential with distance
a) increases b) decreases
c) remains constant d) none of these.
v) Which one is the correct one for muscle force ( M.F. ) ?
a) Active M.F. = Stimulatd M.F + Passive M.F.
b) Active M.F. = Stimulated M.F. – Passive M.F.
c) Active M.F. = Stimulated M.F. / Passive M.F.
d) None of these.
vi) If the capacitive current of a cell membrane I c , membrane capacitance C m and change of membrane potential with time ( t ) is dv m dt , then what will be the membrane current ( I c ) expression ?
vii) The Nernst potential for a particular cation is calculated by the equation [ e = conc. of extra cellular fluid, i = conc. of intra cellular fluid ]
viii) Building block models are derived by applying
a) input-output relationship b) internal functioning of the system c) fundamental laws d) none of these.
ix) O 2 consumption ( ml / min / 100 gm ) in kidney is
a) 2·2 b) 6·8
c) 3·7 d) none of these.
x) The full form of RBR is
a) Renal Vessel Resistance b) Renal Valve Resistance
c) Renal Vascular Resistance d) None of these.
GROUP – B : ( Short Answer Type Questions )
Answer any three of the following. 3 × 5 = 15
2. Describe the model of whole neuron step by step and also apply the Kirchhoff’s current law for each step.
3. Explain the purpose and characteristics of physiological modeling.
4. Describe the linearization process of a non-linear model.
5. Briefly describe the ‘voltage clamp experiment’ done by ‘Hodgkin and Huxley’.
6. Briefly explain about the electrical analogue model of blood flow.
GROUP – C : ( Long Answer Type Questions )
Answer any three of the following questions. 3 × 15 = 45
7. What do you mean by the term ‘immune response’ ? Briefly discuss the linearized model of the immune response to germ cells, plasma cells and antibody. Write down the system equations for the immune response. 3 + 7 + 5
8. What is nerve action potential ? How is it developed ? Draw and briefly discuss about the electrical equivalent circuit of the nerve membrane. Briefly discuss about the step response of ‘Potassium conductance’ with its non-linear model. 3 + 7 + 5
9. a) Explain the time invariant and time varying systems for physiological modeling with example.
b) Describe briefly about the model of coronany circulation.
c) Write down the four compartmental model of bone-cell formation. 6 + 7 + 2
10. a) Write down the cross-bridge theory of muscle contraction.
b) Briefly explain about the Huxley’s model of isotonic muscle contraction. 6 + 9
11. a) Briefly explain about the different types of non-linear model.
b) Why are model specification and estimation important in successful modeling ?
c) Draw the schematic diagram of EMG-modeling and explain it. 5 + 5 + 5
12. a) Describe the model of Henle’s loop for NaCl transport.
b) How do you measure the renal blood flow ( RBF ) ? Write down the equation for renal blood flow. 10 + ( 3 + 2 )
Modelling Of Physiological System – 2013 :
Time Allotted : 3 Hours
Full Marks : 70
** The figures in the margin indicate full marks.
** Candidates are required to give their answers in their own words as far as practicable.
GROUP – A : ( Multiple Choice Type Questions )
1. Choose the correct answer of the following : 10 × 1 = 10
i) In electrical analogue model, pressure changes is considered as
a) Current changes
b) Resistance changes
c) Potential changes
d) None of these.
ii) The nature of urine in proximal tubule is
a) Hypotonic b) Hypertonic
c) Isotonic d) None of these.
iii) Ligament is modelled by
a) Spring
b) Dashpot
c) Combination of spring and dashpot
d) None of these.
iv) The cell membrane potential ………..with distance.
a) increases b) decreases
c) remains constant d) none of these.
v) Which one is the correct one for muscle force (M.F) ?
a) Active M.F = Stimulated M.F. + Passive M.F
b) Active M.F = Stimulated M.F – Passive M.F
c) Active M.F = Stimulated M.F /Passive M.F
d) None of these.
vii) The Nernst potential of ! Na+ is
a) 77 mV b) – 57 mV
c) 67 mV d) – 59·5 mV.
viii) In the modelling of blood flow in circulatory system, the reference or ground point is chosen as
a) Left atrium b) Right atrium
c) Left ventricle d) Right ventricle.
ix) MVC is
a) Minimum voluntary contraction
b) Moderate voluntary contraction
c) Maximum voluntary contraction
d) none of these.
x) The substances which are capable of eliciting an immune response are called
a) antigen b) antibody
c) lymphocytes d) plasma cell.
GROUP – B : ( Short Answer Type Questions )
Answer any three of the following : 3 × 5 = 15
2. Explain the recording technique of nerve action potential.
3. Classify different types of non-linear model with example.
4. Explain the purpose and characteristics of physiological modelling.
5. Describe the linearization process of a nonlinear model.
6. Briefly describe the “voltage clamp experiment” done by Hodgkin and Huxley.
7. Briefly explain about the electrical analogue model of blood flow.