Basic Microbiology, Virology & Immunology M.Sc Non Medical Question Bank : web.tnmgrmu.ac.in

Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : M.Sc Non Medical Degree Examination
Subject Code/Name : 9125/Basic Microbiology, Virology And Immunology
Year : I
Paper : I
Document Type : Question Bank
Website : web.tnmgrmu.ac.in

Download Model/Sample Question Paper :
2011-2012 : https://www.pdfquestion.in/uploads/web.tnmgrmu.ac.in/4037-289125KY.pdf

MAY 2011 :
Sub. Code: 9125
M.Sc MOLECULAR VIROLOGY EXAMINATION
(for Candidates admitted from 2009-2010 onwards)
PAPER I : BASIC MICROBIOLOGY, VIROLOGY AND IMMUNOLOGY
Q.P. Code : 289125
Time : Three hours
Maximum :100marks
Answer All questions. :
I. Elaborate on : (2 x 20 = 40)
1. Enumerate the different methods of Sterilization. Write in detail about autoclave.
2. Explain in detail various levels of Biosafety in a microbiological laboratory. Add a note on BSL 3.
II. Write notes on : (10 x 6 = 60)
1. Guinea Pig.
2. Neutralization test.
3. Fluorescent Microscopy.
4. Decontamination.
5. Chromatography.
6. PCR.
7. Structure / Morphology of Viruses.
8. Hot air oven.
9. Continuous Cell lines.
10. Complement.

Sub. Code: 9125
I. Elaborate on :
1. How will you cultivate and purify virusus both
in-vivo and in-vitro.
2. Describe in detail the various pathways of complement system activation.
II. Write notes on :
1. Containment facilities in a virology laboratory.
2. Ultracentrifugation purification of viruses.
3. Flowcytometry.
4. Confocal microscope principle and application.
5. Chromatography.
6. Signal transduction pathways.
7. Cell line maintenance media.
8. Stem cells.
9. Antibody structure and different immunoglobulin claims.
10. Positive and Negative selection.

Sub. Code: 9125
I. Elaborate on :
1. Classify Hypersensitivity. Discuss in detail the mechanisms of Type I Hypersensitivity with examples
2. Define virus. Enumerate Baltimore Classification. Describe viral replication mechanisms with examples.
II. Write notes on :
1. Polymerase chain reaction and its applications
2. Differences between T and B cells
3. Monoclonal antibodies and its uses
4. Systemic lupus erythematosus
5. Principle of dark ground microscopy
6. Primary lymphoid organs
7. Type IV Hypersensitivity
8. Detection of viral growth in tissue culture
9. Mechanisms of action of Disinfectants
10.Immunoelectrophoresis and its applications

OCTOBER 2013 :
I. Elaborate on : (2X20=40)
1. Discuss in detail the various methods of disinfection.
2. Enumerate on Tissue culture methodologies.
II. Writes notes on: (10X6=60)
1. Gaseous Sterilization
2. Dark field Microscopy
3. Bio-safety Level – 3
4. Antibody structure
5. Interferons
6. Graft Versus Host reaction
7. Handling and maintenance of laboratory animals
8. Ultracentrifugation
9.Karyotyping
10. Gel Electrophoresis.