Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : M.Pharm DEGREE EXAMINATION
BRANCH VI : PHARMACEUTICAL BIOTECHNOLOGY
Subject Code/Name : 2917/Pharmaceutical Aspects Of Microbial And Cellular Biology
Year : I
Paper : II
Document Type : Question Bank
Website : web.tnmgrmu.ac.in
Download Model/Sample Question Paper :
2011-2014 : https://www.pdfquestion.in/uploads/web.tnmgrmu.ac.in/PHARMACY/3872-262917KY.pdf
MAY 2011 :
[KY 356] Sub. Code: 2917
M.PHARM. DEGREE EXAMINATION.
(Regulations 2010)
(Candidates admitted from 2010-2011 onwards)
BRANCH VI : PHARMACEUTICAL BIOTECHNOLOGY
PAPER II : PHARMACEUTICAL ASPECTS OF MICROBIAL AND CELLULAR BIOLOGY
Q.P. Code : 262917
Time : Three hours
Maximum : 100 marks
Answer All questions :
I. Essay Questions : (6 x 10 = 60)
1. Detail about preparation and purification of DiphtheriaToxoid.
2. Classify immunity and explain.
3. Production of interferon’s.
4. Outline about growth curve of bacteria.
5. Write detail about secondary metabolites and its application.
6. Give an account of Humoral and cellular immunity.
II. Write Short Notes : (8 x 5 = 40)
1. Differentiate prokaryotic and eucaryotic microorganism.
2. Function of MHC.
3. Application of cell culture in pharmaceutical industry.
4. Mathematical explanation of bacterial growth.
5. Conjugation.
6. Structure of prokaryotic micro organism.
7. Synthesis of protein.
8. Classify bacteria depend on temperature.
October 2011 :
I. Elaborate on :
1. Explain the structure, chemistry, nutritional requirements and reproduction of bacteria. Add a note on the industrial importance of bacteria.
2. Explain the Animal cell culture media and cultivation of primary culture.
II. Write notes on :
1. Actinomycetes.
2. Bio-energetics and Mechanism of ATP synthesis.
3. Synthesis of DNA.
4. Synthesis of proteins.
5. Hypersensitivity reactions.
6. Auto-immune diseases.
7. Mechanism of microbial pathogenecity.
8. Conjugation and Transduction.
9. Etiology, Pathology and control of any two bacterial diseases.
10. Mutagenesis and its applications in strain improvement.
MAY 2012 :
I. Elaborate on :
1. Elaborate study about microbial sensitive of Klebsiella pneumonia against streptomycin.
2. a. Define immunity and Explain different type of immunity.
b. What is lysogeny? Explain the mechanism of lysogeny.
II. Write notes on:
1. Explain in brief theory of central dogma.
2. Auto immune diseases.
3. Mechanism of action of anti-microbial agents.
4. Various methods of isolation of bacteria.
5. Sexual reproduction in fungi.
6. Synchronous culture.
7. Factor influence the immune response.
8. Method of preservation of culture.
9. Physical and chemical environment of microbial growth.
10. Etiology, pathology and control of tuberculosis.
NOVEMBER 2012 :
I. Elaborate on :
1. Explain the structure, chemistry, morphology and reproduction of fungi. Write the Industrial importance of fungi.
2. Discuss the hypersensitivity reactions and auto immune diseases.
II. Write Notes on :
1. Synthesis of DNA.
2. Animal cell culture media.
3. Conjugation and Transduction.
4. Mechanism of action of anti-microbial agents.
5. Cultivation and enumeration of viruses.
6. Mutagenesis and repair mechanisms.
7. Etiology, Pathology and control of any two viral diseases.
8. Immuno-deficiency diseases.
9. Describe the fuelling reaction of aerobic organisms.
10. Actinomycetes.