Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : M.Pharm DEGREE EXAMINATION
BRANCH V : PHARMACEUTICAL ANALYSIS
Subject Code/Name : 2914/Pharmaceutical And Cosmetic Analysis
Year : I
Paper : II
Document Type : Question Bank
Website : web.tnmgrmu.ac.in
TNMGRMU Pharmaceutical & Cosmetic Analysis Question Bank
[KY 353] Sub. Code: 2914
M.PHARM. DEGREE EXAMINATION : (Regulations 2010)
Related : TNMGRMU Drug Design And Molecular Pharmacology M.Pharm Question Bank : www.pdfquestion.in/3869.html
(Candidates admitted from 2010-2011 onwards)
BRANCH V – PHARMACEUTICAL ANALYSIS
PAPER II – PHARMACEUTICAL AND COSMETIC ANALYSIS
MAY 2011
Q.P. Code : 262914
Time : Three hours
Maximum : 100 marks
Answer All questions :
I. Essay Questions : (6 x 10 = 60)
1. Explain any two drugs official in IP assay principle and procedure by UV and HPLC method.
2. Describe about ICH guidelines for impurities.
3. Explain any two preservatives identification and quantification test.
4. Discuss about ISI specification of quality of perfumes and colourants raw materials used in cosmetics.
5. Explain toxicity testing of cosmetics.
6. Discuss about ISI specification of high grade soap.
II. Write Short Notes : (8 x 5 = 40)
1. Antioxidants used in pharmaceuticals.
2. Radio chemical methods in analysis.
3. Accelerative stability studies.
4. QC of injections.
5. ISI specification of nail polish.
6. ISI specification of skin powders
7. Surfactants raw material used in cosmetics.
8. ISI specification of baby shampoo.
Download Model/Sample Question Paper :
2011-2014 :
https://www.pdfquestion.in/uploads/web.tnmgrmu.ac.in/PHARMACY/3870-1-262914KY.pdf
1991-2011 :
https://www.pdfquestion.in/uploads/web.tnmgrmu.ac.in/PHARMACY/3870-2-262864KX.pdf
OCTOBER 2011
I. Elaborate on :
1. Explain the principle and procedure involved in the official assay of (i). Allopurinol (ii). Metronidzol (iii) Piperazine 4. Verapamil.
2. Write a note on different raw materials used in cosmetics?
II. Write notes on :
1. How will you perform the test for toxicity in cosmetics?
2. Enumerate the Indian Standard specifications of nail polish?
3. List out the various Quality control test of tablets?
4. Describe about the water raw material purification methods involved in quality control?
5. Enumerate in detail about the sampling process of biological sample?
6. Identification and Quantitative determination of any two preservatives?
7. Write an account on cosmetic legislation?
8. Describe the quality control tests for ointments?
9. Explain the diazotization titration with example?
10. Explain the principle and procedure involved in the IP official assay of (i) Ibuprofen (ii) Tolbutamide.
MAY 2012
I. Elaborate on:
1. Write in detail discussion on in process quality control test for the following pharmaceutical dosage forms (i) Parenterals (ii) Tablets.
2. Explain the different methods of analysis to assess the quality of the following cosmetic products.
(i) Lipsticks (ii) Hair care Products (iii) Baby Powder (iv) Dental products.
II. Write notes on :
1. Explain principle and procedure involved in the official (IP 1996) assays of (i) Calcium gluconate tablets (ii) Chloramphenicol eye drops.
2. List out different solvents used in cosmetics and discuss quality control test for any one of solvent used in cosmetics.
3. How do you determine microbial contamination in cosmetics?
4. Explain the method of identification and determination of any two antioxidants.
5. Write ICH guidelines for related substance and impurity detection in drugs.
6. Explain toxicity testing of cosmetics.
7. BIS specification for Shampoo.
8. Discuss in process quality control test for ointments.
9. Discuss ICH guidelines for stability studies of drugs.
10. Explain various extraction process involved in biological sample analysis and their limitation and applications.
NOVEMBER 2012
I. Elaborate on :
1. In detail explain the identification and qualitative determination of antioxidants used in pharmaceutical preparations.
2. What are the procedures used for the extraction of drugs from biological samples and explain the factors affecting extraction procedures.
II. Write Notes on :
1. How is the toxicity testing done for cosmetics?
2. Write the method for determination of related substances present in metronidazole IP and paracetamol IP.
3. What are the in process quality control tests carried out for different types of capsules?
4. What are radio pharmaceuticals? How does the quality of them determined?
5. What re the raw materials used in cosmetics? Explain quality control two of them.
6. How is the QC test for controlled release dosage forms performed?
7. List out the preservatives used in pharmaceutical preparations, giving their limit and estimation procedures.
8. Explain with few examples how the Complexometric titration utilized for the estimation of official compounds.
9. What is shelf life of formulations? How shelf life is predicted with accelerated stability testing?
10. Write on testing of color cosmetics.